分子序成像

脂类分子序成像:

BondXplorer microscope 可与分解偏振测量方法相结合,对复杂系统(如小鼠髓磷脂鞘)中的化学键进行定向。

BondXplorer microscope 分解偏振成像,显示小鼠髓磷脂鞘中C-H键的极化方向。 图像大小 150 µm x 150 µm。

Publications:

  • P. Gasecka, A. Jaouen, F.-Z. Bioud, H. B. de Aguiar, J. Duboisset, P. Ferrand, H. Rigneault, N. K. Balla, F. Debarbieux, and S. Brasselet, “Lipid Order Degradation in Autoimmune Demyelination Probed by Polarized Coherent Raman Microscopy,” Biophysical Journal 113, 1520-1530 (2017). doi.org/10.1016/j.bpj.2017.07.033
  • C. Cleff, A. Gasecka, P. Ferrand, H. Rigneault, S. Brasselet, and J. Duboisset, “Direct imaging of molecular symmetry by coherent anti-stokes Raman scattering,” Nat Commun 7, 11562 (2016). doi.org/10.1038/ncomms11562