Metabolic Imaging

Mapping the expression of deuterated proteins and lipids

Lightcore Technologies BondXplorer microscope can image deuterated molecules expression in complex living systems, taking advantage of its ability to detect simultaneously two wavenumbers (signal and noise).


Distinguishing Bacteria Groups

BondXplorer: Green: deuterated bacteria; Red: non deuterated bacteria

CH2, CH3 and CD imaging in drosophila fed with deuterated yeast


Publications:

S. Heuke, I. Rimke, B. Sarri, P. Gasecka, R. Appay, L. Legoff, P. Volz, E. Büttner, and H. Rigneault, “Shot-noise limited tunable dual-vibrational frequency stimulated Raman scattering microscopy,” Biomed. Opt. Express 12, 7780-7789 (2021). https://doi.org/10.1364/BOE.446348 SMASH