Medical / Biomedical Applications

Instantaneous Histology

You are a clinical practitioner, a pathologist, or a scientist that desires histological information from a fresh biopsy tissue.

Lightcore Technologies BondXplorer microscope provides immediate label-free histological imaging over mm2 field of view in a few minutes only.

” No sample preparation, no staining, instantaneous label-free histology is possible with our BondXplorer microscope. “

All brain tumors

one drop of water

Applicable to any organs

Live Histology

Choose the Live Mode and explore your whole sample in real time


  • R. Appay, B. Sarri, S. Heuke, S. Boissonneau, C. Liu, E. Dougy, L. Daniel, D. Scavarda, H. Dufour, D. Figarella-Branger, and H. Rigneault, “Live Stimulated Raman Histology for the Near-Instant Assessment of Central Nervous System Samples,” The Journal of Physical Chemistry B 127, 3624-3631 (2023).
  • B. Sarri, R. Appay, S. Heuke, F. Poizat, F. Franchi, S. Boissonneau, F. Caillol, H. Dufour, D. Figarella-Branger, M. Giovaninni, and H. Rigneault, “Observation of the compatibility of stimulated Raman histology with pathology workflow and genome sequencing,” Translational Biophotonics n/a, e202000020 (2021).
  • B. Sarri, F. Poizat, S. Heuke, J. Wojak, F. Franchi, F. Caillol, M. Giovannini, and H. Rigneault, “Stimulated Raman histology: one to one comparison with standard hematoxylin and eosin staining,” Biomed. Opt. Express 10, 5378-5384 (2019). SMASH
  • B. Sarri, R. Canonge, X. Audier, E. Simon, J. Wojak, F. Caillol, C. Cador, D. Marguet, F. Poizat, M. Giovannini, and H. Rigneault, “Fast stimulated Raman and second harmonic generation imaging for intraoperative gastro-intestinal cancer detection,” Scientific Reports 9, 10052 (2019). SMASH