Chemical Imaging / Pharmaceutical Sciences

Mapping Drug Distribution in Pharmaceutical Products

You are a chemical scientist and you want to image in a label-free manner chemical compounds in complex formulation or pharmaceutical tablets. Lightcore Technologies BondXplorer microscope provides a versatile and tunable platform to image chemical compounds through their vibrational signatures [350cm-1, 3800cm-1].

BondXplorer: Image of pharmaceutical tablet containing three excipients (PEG, Manitol, Starch) and two polymorph active molecules (A-F1 and A-F2).

Publications

  • B. Sarri, R. Canonge, X. Audier, V. Lavastre, G. Pénarier, J. Alie, and H. Rigneault, “Discriminating polymorph distributions in pharmaceutical tablets using stimulated Raman scattering microscopy,” Journal of Raman Spectroscopy 50, 1896-1904 (2019). doi.org/10.1002/jrs.5743